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KMID : 0921620090390020097
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Journal of Bacteriology and Virology
2009 Volume.39 No. 2 p.97 ~ p.102
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Antimicrobial Activity of Methanol Extract from Ficus carica Leaves Against Oral Bacteria
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Jeong Mi-Ran
Kim Hye-Young
Cha Jeong-Dan
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Abstract
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Ficus carica L. (fig) belongs to the mulberry tree (Moraceae) which is one of the oldest fruits in the world. It has been used as a digestion promoter and a cure for ulcerative inflammation and eruption in Korea. The present study investigated the antimicrobial activity of methanol (MeOH) extract of figs against oral bacteria. The MeOH extract (MICs, 0.156 to 5 mg/ml; MBCs, 0.313 to 5 mg/ml) showed a strong antibacterial activity against oral bacteria. The combination effects of MeOH extract with ampicillin or gentamicin were synergistic against oral bacteria. We suggest that figs could be employed as a natural antibacterial agent in oral care products.
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KEYWORD
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Ficus carica (fig), Antibacterial activity, MIC/MBC, Synergistic
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